PredicND is a four-year, €4.2 m European project focusing on developing tools and means for earlier, evidence-based diagnosis of a range of neurodegenerative diseases. PredictND consortium members include Alzheimer Europe (Luxembourg), Combinostics Ltd. (Finland), GE Healthcare (UK, Sweden), Imperial College of London (UK), Rigshospitalet (Denmark), Università degli Studi di Perugia (Italy), University of Eastern Finland (Finland), VTT Technical Research Centre of Finland Ltd. (Finland) (coordinator) and VU/VUmc (the Netherlands).
BrainStem – Stem Cell Center of Excellence in Neurology
BrainStem – Stem Cell Center of Excellence in Neurology is supported by Innovation Fund Denmark. The project coordinator is Professor Poul Hyttel, University of Copenhagen and its primary partners are the University of Copenhagen, Lund University (Sweden), DDRC at Rigshospitalet, University of Southern Denmark, Aarhus University (Denmark), Bioneer (Denmark), Lundbeck A/S (Denmark) and Innovative Concepts in Drug Development (France). Advanced stem cell technologies are used to re-programme skin cells from patients with AD and Parkinson’s disease to diseased neurons to investigate the molecular mechanisms, to develop better diagnostics and to test new drugs.
Frontotemporal Dementia Research in Jutland Association (FReJA)
FReJA is an international multidisciplinary consortium established more than a decade ago to investigate a unique, large FTD-3 family in western Jutland. Basic and clinical scientists in Denmark, Sweden and the UK have made major progress over the years in identifying the disease gene and in understanding the disease mechanisms and their wider relevance for neurodegeneration in general.
European Alzheimer’s Disease Consortium (EADC)
EADC is a network of more than 50 European academic centres of excellence working in the field of AD and other dementias. It provides a forum for expanding scientific understanding and development of ways to prevent, delay, slow or ameliorate the primary and secondary symptoms of AD. The European Commission provided initial funding for EADC and supports working towards standardisation of diagnostic criteria, assessment tools and data collection methods, with a view to this being followed by a trial period involving the testing and practical application of the tools agreed upon (see eadc.info/sito/pagine/ home.php). The only Danish EADC member, DDRC has contributed to or directed studies on assessment tools, health economics, biomarkers and cross-cultural aspects of dementia care. DDRC hosted the biannual EADC meating in Copenhagen in November 2016.
DDRC takes part in Interdem, a pan-European network of researchers collaborating in research on and dissemination of early, timely and quality psychosocial interventions aimed at improving the quality of life across Europe for people with dementia and their supporters. Members of the network include academic and clinical researchers from 23 nations. DDRC hosted the annual Interdem meeting in Copenhagen in November 2016.
Nordic Network in Dementia Diagnostics (NIDD)
NIDD is funded by the Nordic Council and comprises eight academic memory clinics in the Nordic countries and Lithuania. As the name indicates, the main objective of the network is to examine various aspects of diagnostic procedures in dementia. DDRC and the memory clinic at Roskilde Hospital are the network’s Danish partners.
European Huntington’s Disease Network (EHDN) and Enroll HD
DDRC is part of EHDN, which provides a platform for professionals and people affected by HD and their relatives to facilitate collaboration throughout Europe. DDRC’s staff and patients with HD have contributed significantly to clinical cohort studies and intervention studies. Enroll-HD, initiated in 2012, is the world’s largest observational study for HD families. The study is designed as a clinical research platform that will enable healthcare professionals, scientists and families affected by HD to work together towards an improved understanding of HD and better care and treatments. At the close of 2016, DDRC’s Enroll-HD cohort comprised 206 participants.
National dementia research and education centres in Scandinavia
Norway, Sweden and Denmark have national non-profit dementia research and education centres commissioned and funded by the national boards or ministries of health. DDRC, the Norwegian Centre for Dementia Research and the Swedish Dementia Centre collaborate and meet annually to share ideas and exchange programmes for the benefit of professional care staff, persons with dementia and family caregivers throughout Scandinavia. A sizeable conference on leadership in dementia care is one of the larger outcomes of this Scandinavian collaboration. The conference is held every other year.
North Sea Dementia Group
The North Sea Dementia Group is an association of interested persons from dementia care practice and research. The theme of this year’s meeting in Scotland was Dementia Aware Societies. The meeting included visits to care homes and day care centres.
Joint Programming on Neurodegenerative Diseases (JPND)
Funded by Horizon 2020 and EU member states the JPND is an innovative collaborative research initiative established to tackle neurodegeneratrive diseases. DDRC has taken part in three JPND funded research consortia on biomarkers in Alzheimer’s and Parkonson’s diseases (BIOMARKAPD), on definition of outcome measures in dementia and on harmonization of assessment methods.