Til forsiden

2016

Academic articles published by scientists affiliated with the Danish Dementia Research Centre in 2016 are presented below:

Bertelsen, B, Nazaryan, L, Sun, W, Mehrjouy, MM, Xie, G, Chen, W, Hjermind, LE, Taschner, PEM & Tümer, Z. A germline chromothripsis event stably segregating in 11 individuals through three generations. Genetics in medicine 2016; nr. 18: 494-500.

Chaaya, M, Phung, TKT, El Asmar, K, Atweh, S, Ghusn, H, Khoury, RM, Prince, M, Nielsen, TR & Waldemar, G. Validation of the Arabic Rowland Universal Dementia Assessment Scale (A-RUDAS) in elderly with mild and moderate dementia. Aging & Mental Health 2016; 20: 880-7.

Falkentoft, AC & Hasselbalch, SG. Immunterapi mod Alzheimers sygdom. Ugeskrift for Læger 2016; 178: V07150588.

Ferreira, D, Jelic, V, Cavallin, L, Oeksengaard, A-R, Snaedal, J, Høgh, P, Andersen, BB, Naik, M, Engedal, K, Westman, E & Wahlund, L-O. Electroencephalography Is a Good Complement to Currently Established Dementia Biomarkers. Dementia and Geriatric Cognitive Disorders 2016;
42: 80-92.

Hansen, SK, Stummann, TC, Borland, H, Hasholt, LF, Tümer, Z, Nielsen, JE, Rasmussen, MA, Nielsen, TT, Daechsel, JCA, Fog, K & Hyttel, P. Induced pluripotent stem cell-derived neurons for the study of spinocerebellar ataxia type 3. Stem Cell Research 2016; 17: 306-317.

Hansen, SK, Borland, H, Hasholt, LF, Tümer, Z, Nielsen, JE, Rasmussen, MA, Nielsen, TT, Stummann, TC, Fog, K & Hyttel, P. Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.B11. Stem Cell Research 2016; 16: 589-92.

Hansen, SK, Borland, H, Hasholt, LF, Tümer, Z, Nielsen, JE, Rasmussen, MA, Nielsen, TT, Stummann, TC, Fog, K & Hyttel, P. Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.A11. Stem Cell Research 2016; 16: 553-6.

Hoffmann, K, Sobol, NA, Frederiksen, KS, Beyer, N, Vogel, A, Vestergaard, K, Brændgaard, H, Gottrup, H, Lolk, A, Wermuth, L, Jacobsen, S, Laugesen, LP, Gergelyffy, RG, Høgh, P, Bjerregaard, E, Andersen, BB, Siersma, V, Johannsen, P, Cotman, CW, Waldemar, G & Hasselbalch, SG. Moderate-to-High Intensity Physical Exercise in Patients with Alzheimer’s Disease: A Randomized Controlled Trial. Journal of Alzheimer’s disease
2016; 50: 443-53.

Jensen, CG, Niclasen, J, Vangkilde, SA, Petersen, A & Hasselbalch, SG. General inattentiveness is a long-term reliable trait independently predictive of psychological health: Danish validation studies of the Mindful Attention Awareness Scale. Psychological Assessment 2016; 28: e70-87.

Jensen, CG, Hjordt, LV, Stenbæk, DS, Andersen, E, Back, SK, Lansner, J, Hageman, I, Dam, OH, Nielsen, AP, Knudsen, GM, Frokjaer, VG & Hasselbalch, SG. Development and psychometric validation of the verbal affective memory test. Memory 2016: 1208-23.

Jensen-Dahm, C, Madsen, CS, Waldemar, G, Ballegaard, M, Hejl, A-M, Johnsen, B & Jensen, TS. Contact Heat Evoked Potentials (CHEPs) in
Patients with Mild-Moderate Alzheimer’s Disease and Matched Control-A Pilot Study. Pain medicine 2016; 17: 675-84.

Jensen-Dahm, C, Palm, H, Gasse, C, Dahl, JB & Waldemar, G. Postoperative Treatment of Pain after Hip Fracture in Elderly Patients with Dementia.
Dementia and Geriatric Cognitive Disorders 2016; 41: 181-91.

Jørgensen, K, Hasselbalch, SG & Waldemar, G. Risiko for demens og kognitiv svækkelse kan reduceres. Ugeskrift for Læger 2016; 178: V11150887.

Knudsen, GM, Jensen, PS, Erritzoe, D, Baaré, WFC, Ettrup, A, Fisher, PM, Gillings, N, Hansen, HD, Hansen, LK, Hasselbalch, SG, Henningsson, S, Herth, MM, Holst, KK, Iversen, P, Kessing, LV, Macoveanu, J, Madsen, KS, Mortensen, EL, Nielsen, FÅ, Paulson, OB, Siebner, HR, Stenbæk, DS,
Svarer, C, Jernigan, TL, Strother, SC & Frokjaer, VG. The Center for Integrated Molecular Brain Imaging (Cimbi) database. NeuroImage 2016;
124: 1213-1219.

Koikkalainen, J, Rhodius-Meester, H, Tolonen, A, Barkhof, F, Tijms, B, Lemstra, AW, Tong, T, Guerrero, R, Schuh, A, Ledig, C, Rueckert, D, Soininen, H, Remes, AM, Waldemar, G, Hasselbalch, S, Mecocci, P, van der Flier, W & Lötjönen, J. Differential diagnosis of neurodegenerative diseases using
structural MRI data. NeuroImage 2016. Clinical; 11: 435-49.

Larsen, IU, Vinther-Jensen, T, Gade, A, Nielsen, JE & Vogel, A. Do I Misconstrue?: Sarcasm Detection, Emotion Recognition, and Theory of Mind in Huntington Disease. Neuropsychology 2016; 30: 181-189.

Larsen, IU, Mortensen, EL, Vinther-Jensen, T, Nielsen, JE, Knudsen, GM & Vogel, A. Personality traits in Huntington. s disease: An exploratory study of gene expansion carriers and non-carriers. American journal of medical genetics 2016; 171: 1153-1160.

Larsen, IU, Vinther-Jensen, T, Nielsen, JE, Gade, A & Vogel, A. Social Cognition, Executive Functions and Self-Report of Psychological Distress in Huntington. s Disease. PLOS Currents Huntington Disease 2016; 8: E1-10.

Leuzy, A, Chiotis, K, Hasselbalch, SG, Rinne, JO, de Mendonça, A, Otto, M, Lleó, A, Castelo-Branco, M, Santana, I, Johansson, J, Anderl-Straub, S, von Arnim, CAF, Beer, A, Blesa, R, Fortea, J, Herukka, S-K, Portelius, E, Pannee, J, Zetterberg, H, Blennow, K & Nordberg, A. Pittsburgh compound B imaging and cerebrospinal fluid amyloid-ß in a multicentre European memory clinic study. Brain 2016; 139: 2540-53.

Li, T, Pires, C, Nielsen, TT, Waldemar, G, Hjermind, LE, Nielsen, JE, Dinnyes, A, Holst, B, Hyttel, P & Freude, KK. Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer’s disease patient carrying a M146I mutation in PSEN1. Stem Cell Research 2016; 16: 334-7.

Li, T, Pires, C, Nielsen, TT, Waldemar, G, Hjermind, LE, Nielsen, JE, Dinnyes, A, Hyttel, P & Freude, KK. Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer’s disease patient carrying an A79V mutation in PSEN1. Stem Cell Research 2016; 16: 229-32.

Marthaler, AG, Schmid, B, Tubsuwan, A, Poulsen, UB, Hyttel, P, Nielsen, TT, Nielsen, JE & Holst, B. Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H196. Stem Cell Research 2016; 16: 199201.

Marthaler, AG, Tubsuwan, A, Schmid, B, Poulsen, UB, Engelbrecht, AF, Mau-Holzmann, UA, Hyttel, P, Nielsen, TT, Nielsen, JE & Holst, B. Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H266. Stem Cell Research 2016; 16: 202-5.

Marthaler, AG, Schmid, B, Tubsuwan, A, Poulsen, UB, Engelbrecht, AF, Mau-Holzmann, UA, Hyttel, P, Nielsen, JE, Nielsen, TT & Holst, B. Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H271. Stem Cell Research 2016; 16: 180-3.

Marthaler, AG, Schmid, B, Tubsuwan, A, Poulsen, UB, Hyttel, P, Nielsen, TT, Nielsen, JE & Holst, B. Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266. Stem Cell Research 2016; 16: 166-9. Marthaler, AG, Schmid, B, Tubsuwan, A, Poulsen, UB, Engelbrecht, AF, Mau-Holzmann, UA, Hyttel, P, Nielsen, JE, Nielsen, TT & Holst, B. Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H196. Stem Cell Research 2016; 16: 162-5.

Marthaler, AG, Tubsuwan, A, Schmid, B, Poulsen, UB, Hyttel, P, Nielsen, JE, Nielsen, TT & Holst, B. Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H271. Stem Cell Research 2016; 16: 159-61.

Nielsen, TR, Phung, TKT, Chaaya, M, Mackinnon, A & Waldemar, G. Combining the Rowland Universal Dementia Assessment Scale and the Informant Questionnaire on Cognitive Decline in the Elderly to Improve Detection of Dementia in an Arabic-Speaking Population. Dementia and Geriatric Cognitive Disorders 2016; 41: 46-54.

Nielsen, TR & Waldemar, G. Knowledge and perceptions of dementia and Alzheimer. s disease in four ethnic groups in Copenhagen, Denmark. International Journal of Geriatric Psychiatry 2016; 31: 222-30. Nielsen, TR & Waldemar, G. Effects of literacy on semantic verbal fluency in an immigrant population. Aging, Neuropsychology and Cognition 2016; 23: 578-90.

Nielsen, SMB, Vinther-Jensen, T, Nielsen, JE, Nørremølle, A, Hasholt, L, Hjermind, LE & Josefsen, K. Liver function in Huntington. s disease assessed by blood biochemical analyses in a clinical setting. Journal of the Neurological Sciences 2016; 362: 326-32.

Nielsen, ABS, Siersma, V, Waldemar, G & Waldorff, FB. Poor self-rated health did not increase risk of permanent nursing placement or mortality in people with mild Alzheimer. s disease. BMC Geriatrics 2016; 16: 87.

Nimsanor, N, Poulsen, U, Rasmussen, MA, Clausen, C, Mau-Holzmann, UA, Nielsen, JE, Nielsen, TT, Hyttel, P, Holst, B & Schmid, B. Generation of
an isogenic, gene-corrected iPSC line from a pre-symptomatic 28-yearold woman with an R406W mutation in the microtubule associated protein tau (MAPT) gene. Stem Cell Research 2016; 17: 600-602.

Nimsanor, N, Poulsen, U, Rasmussen, MA, Clausen, C, Mau-Holzmann, UA, Nielsen, JE, Nielsen, TT, Hyttel, P, Holst, B & Schmid, B. Generation of an isogenic, gene-corrected iPSC line from a symptomatic 59-year-old female patient with frontotemporal dementia caused by an R406W mutation in the microtubule associated protein tau (MAPT) gene. Stem Cell Research 2016; 17: 576-9.

Nimsanor, N, Jørring, I, Rasmussen, MA, Clausen, C, Mau-Holzmann, UA, Kitiyanant, N, Nielsen, JE, Nielsen, TT, Hyttel, P, Holst, B & Schmid, B. Induced pluripotent stem cells (iPSCs) derived from a symptomatic carrier of a S305I mutation in the microtubule-associated protein tau (MAPT)-gene causing frontotemporal dementia. Stem Cell Research 2016; 17: 564-7.

Nimsanor, N, Kitiyanant, N, Poulsen, U, Rasmussen, MA, Clausen, C, Mau-Holzmann, UA, Nielsen, JE, Nielsen, TT, Hyttel, P, Holst, B & Schmid,
B. Generation of an isogenic, gene-corrected iPSC line from a symptomatic 57-year-old female patient with frontotemporal dementia caused by a P301L mutation in the microtubule associated protein tau (MAPT) gene. Stem Cell Research 2016; 17: 556-559.

Nørgaard, A, Jensen-Dahm, C, Gasse, C, Hansen, HV & Waldemar, G. Time Trends in Antipsychotic Drug Use in Patients with Dementia: A Nationwide Study. Journal of Alzheimer’s Disease 2016; 49: 211-20.

Pires, C, Schmid, B, Petræus, C, Poon, A, Nimsanor, N, Nielsen, TT, Waldemar, G, Hjermind, LE, Nielsen, JE, Hyttel, P & Freude, KK. Generation of a gene-corrected isogenic control cell line from an Alzheimer’s disease patient iPSC line carrying a A79V mutation in PSEN1. Stem Cell Research
2016; 17: 285-8.

Poon, A, Li, T, Pires, C, Nielsen, TT, Nielsen, JE, Holst, B, Dinnyes, A, Hyttel, P & Freude, KK. Derivation of induced pluripotent stem cells from a familial Alzheimer. s disease patient carrying the L282F mutation in presenilin 1. Stem Cell Research 2016; 17: 470-473.

Poon, A, Schmid, B, Pires, C, Nielsen, TT, Hjermind, LE, Nielsen, JE, Holst, B, Hyttel, P & Freude, KK. Generation of a gene-corrected isogenic control
hiPSC line derived from a familial Alzheimer’s disease patient carrying a L150P mutation in presenilin 1. Stem Cell Research 2016; 17: 466-469.

Rasmussen, MA, Hjermind, LE, Hasholt, LF, Waldemar, G, Nielsen, JE, Clausen, C, Hyttel, P & Holst, B. Induced pluripotent stem cells (iPSCs) derived from a pre-symptomatic carrier of a R406W mutation in microtubule-associated protein tau (MAPT) causing frontotemporal dementia. Stem Cell Research 2016; 16: 105-9.

Rasmussen, MA, Hjermind, LE, Hasholt, LF, Waldemar, G, Nielsen, JE, Clausen, C, Hyttel, P & Holst, B. Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a R406W mutation in microtubule-associated protein tau (MAPT). Stem Cell Research 2016; 16: 5-8.

Rasmussen, MA, Hjermind, LE, Hasholt, LF, Waldemar, G, Nielsen, JE, Clausen, C, Hyttel, P & Holst, B. Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT). Stem Cell Research 2016; 16: 70-4.

Schjønning Nielsen, M, Simonsen, AH, Siersma, V, Hasselbalch, SG & Høgh, P. Are CSF Biomarkers Useful as Prognostic Indicators in Diagnostically
Unresolved Cognitively Impaired Patients in a Normal Clinical Setting. Dementia and Geriatric Cognitive Disorders Extra 2016; 6: 465-476.

Schütt, T, Helboe, L, Pedersen, LØ, Waldemar, G, Berendt, M & Pedersen, JT. Dogs with Cognitive Dysfunction as a Spontaneous Model for Early Alzheimer. s Disease: A Translational Study of Neuropathological and Inflammatory Markers. Journal of Alzheimer’s Disease 2016; 52: 433-49.

Simonsen, AH, Kuiperij, B, El-Agnaf, OMA, Engelborghs, S, Herukka, S-K, Parnetti, L, Rektorova, I, Vanmechelen, E, Kapaki, E, Verbeek, M & Mollenhauer, B. The utility of a-synuclein as biofluid marker in neurodegenerative diseases: a systematic review of the literature. Biomarkers in
Medicine 2016; 10: 19-34.

Sobol, NA, Hoffmann, K, Vogel, A, Lolk, A, Gottrup, H, Høgh, P, Hasselbalch, SG & Beyer, N. Associations between physical function, dualtask performance and cognition in patients with mild Alzheimer’s disease. Aging & Mental Health 2016; 20: 1139-46.

Sobol, NA, Hoffmann, K, Frederiksen, KS, Vogel, A, Vestergaard, K, Brændgaard, H, Gottrup, H, Lolk, A, Wermuth, L, Jakobsen, S, Laugesen, L, Gergelyffy, R, Høgh, P, Bjerregaard, E, Siersma, V, Andersen, BB, Johannsen, P, Waldemar, G, Hasselbalch, SG & Beyer, N. Effect of aerobic
exercise on physical performance in patients with Alzheimer’s disease.

Alzheimer’s & Dementia 2016; 12: 1207-1215. Steen Jensen, C, Portelius, E, Siersma, V, Høgh, P, Wermuth, L, Blennow, K, Zetterberg, H, Waldemar, G, Hasselbalch, S & Hviid Simonsen, A. Cerebrospinal Fluid Amyloid Beta and Tau Concentrations Are Not Modulated by 16 Weeks of Moderate- to High-Intensity Physical Exercise in Patients with Alzheimer Disease. Dementia and Geriatric Cognitive Disorders 2016; 42: 146-158.

Stenbæk, DS, Einarsdottir, HS, Goregliad-Fjaellingsdal, T, Knudsen, GM, Frokjaer, VG & Hasselbalch, SG. Evaluation of acute tryptophan depletion and sham depletion with a gelatin-based collagen peptide protein mixture. Journal of European College of Neuropsychopharmacology 2016; 26: 147-9.

tevnsborg, L, Jensen-Dahm, C, Nielsen, TR, Gasse, C & Waldemar, G. Inequalities in Access to Treatment and Care for Patients with Dementia and Immigrant Background: A Danish Nationwide Study. Journal of Alzheimer’s Disease 2016; 54: 505-14.

Tubsuwan, A, Pires, C, Rasmussen, MA, Schmid, B, Nielsen, JE, Hjermind, LE, Hall, V, Nielsen, TT, Waldemar, G, Hyttel, P, Clausen, C, Kitiyanant, N, Freude, KK & Holst, B. Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer. s disease patient carrying a L150P mutation in PSEN-1. Stem Cell Research 2016; 16: 110-2.

Vinther-Jensen, T, Börnsen, L, Budtz-Jørgensen, E, Ammitzbøll, C, Larsen, IU, Hjermind, LE, Sellebjerg, F & Nielsen, JE. Selected CSF biomarkers indicate no evidence of early neuroinflammation in Huntington disease. Neurology: Neuroimmunology & neuroinflammation 2016; 3: e287.

Vinther-Jensen, T, Nielsen, TT, Budtz-Jørgensen, E, Larsen, IU, Hansen, MM, Hasholt, L, Hjermind, LE, Nielsen, JE & Nørremølle, A. Psychiatric and cognitive symptoms in Huntington. s disease are modified by polymorphisms in catecholamine regulating enzyme genes. Clinical Genetics; 89: 320-7.

Vogel, A, Salem, LC, Andersen, BB & Waldemar, G. Differences in quantitative methods for measuring subjective cognitive decline – results from a prospective memory clinic study. International Psychogeriatrics 2016; 28: 1513-20.

Winblad, B, Amouyel, P, Andrieu, S, Ballard, C, Brayne, C, Brodaty, H, Cedazo-Minguez, A, Dubois, B, Edvardsson, D, Feldman, H, Fratiglioni, L, Frisoni, GB, Gauthier, S, Georges, J, Graff, C, Iqbal, K, Jessen, F, Johansson, G, Jönsson, L, Kivipelto, M, Knapp, M, Mangialasche, F, Melis, R, Nordberg, A, Rikkert, MO, Qiu, C, Sakmar, TP, Scheltens, P, Schneider, LS, Sperling, R, Tjernberg, LO, Waldemar, G, Wimo, A & Zetterberg, H. Defeating Alzheimer. s disease and other dementias: a priority for European science and society. The Lancet Neurology 2016; 15: 455-532.

Zakarias, JK, Jensen-Dahm, C, Nørgaard, A, Stevnsborg, L, Gasse, C, Andersen, BG, Søren, J, Waldorff, FB, Moos, T & Waldemar, G. Geographical Variation in Antipsychotic Drug Use in Elderly Patients with Dementia: A Nationwide Study. Journal of Alzheimer’s Disease 2016; 54: 11831192.

Zhang, Y, Schmid, B, Nielsen, TT, Nielsen, JE, Clausen, C, Hyttel, P, Holst, B & Freude, KK .Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific heterozygous mutation in CHMP2B. Stem Cell Research 2016; 17: 148-150.

Zhang, Y, Schmid, B, Nielsen, TT, Nielsen, JE, Clausen, C, Hyttel, P, Holst, B & Freude, KK. Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific homozygous mutation in CHMP2B. Stem Cell Research 2016; 17: 151-153.

Zwan, MD, Rinne, JO, Hasselbalch, SG, Nordberg, A, Lleó, A, Herukka, S-K, Soininen, H, Law, I, Bahl, JMC, Carter, SF, Fortea, J, Blesa, R, Teunissen, CE, Bouwman, FH, van Berckel, BNM & Visser, PJ. Use of amyloidPET to determine cutpoints for CSF markers: A multicenter study. Neurology 2016; 86: 50-8. 

Contributions to Multicentre Studies (European Huntington’s Disease Network)

Cubo, E, Ramos-Arroyo, MA, Martinez-Horta, S, Martínez-Descalls, A, Calvo, S, Gil-Polo, C, European HD Network. Clinical manifestations of
intermediate allele carriers in Huntington disease. Neurology 2016; 87: 571-8.

Dale, M, Maltby, J, Shimozaki, S, Cramp, R, Rickards, H, REGISTRY Investigators of the European Huntington’s Disease Network. Disease stage, but not sex, predicts depression and psychological distress in Huntington's disease: A European population study. Journal of Psychosomatic Research 2016; 80: 17-22.

Senest opdateret: 31. March 2017