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Dissertations

Dissertations written by scientists affiliated with the Danish Dementia Research Centre:
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Ph.D. Dissertation

Rostgaard, N. Frontotemporal Dementia Linked to Chromosome 3:
Markers, Modifiers and Mechanisms. University of Copenhagen 2017.

Scientific papers

Bos, I, Vos, SJ, Frölich, L, Kornhuber, J, Wiltfang, J, Maier, W, Peters, O, Rüther, E, Engelborghs, S, Niemantsverdriet, E, De Roeck, EE, Tsolaki, M, Freund-Levi, Y, Johannsen, P, Vandenberghe, R, Lleó, A, Alcolea, D, Frisoni, GB, Galluzzi, S, Nobili, F, Morbelli, S, Drzezga, A, Didic, M, van Berckel, BN, Salmon, E, Bastin, C, Dauby, S, Santana, I, Baldeiras, I, de Mendonça, A, Silva, D, Wallin, A, Nordlund, A, Coloma, PM, Wientzek, A, Alexander, M, Novak, GP, Gordon, MF, Wallin, ÅK, Hampel, H, Soininen, H, Herukka, S-K, Scheltens, P, Verhey, FR, Visser, PJ & Alzheimer’s Disease Neuroimaging Initiative. The frequency and influence of  dementia risk factors in prodromal Alzheimer’s disease, Neurobiology of aging 2017; 56: 33-40.

Chaaya, M, Phung, K, Atweh, S, El Asmar, K, Karam, G, Khoury, R, Ghandour, L, Ghusn, H, Assaad, S, Prince, M & Waldemar, G. Dementia and family burden of care in Lebanon. British Journal of Psychology Open 2017; 14: 7-9. Chaaya, M, Phung, K, Atweh, S, El Asmar, K, Karam, G, Khoury, R, Ghandour, L, Ghusn, H, Assaad, S, Prince, M & Waldemar, G. Socio-demographic and cardiovascular disease risk facors associated with dementia: Results of a cross-sectional study from Lebanon. Preventive Medicine Reports 2017; 9: 1-5.

Clayton, EL, Mancuso, R, Nielsen, TT, Mizielinska, S, Holmes, H, Powell, N, Norona, F, Overgaard Larsen, J, Milioto, C, Wilson, KM, Lythgoe, MF, Ourselin, S, Nielsen, JE, Johannsen, P, Holm, I, Collinge, J, Frej, A, Oliver, PL, Gomez-Nicola, D & Isaacs, AM. Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementiacausing CHMP2B mutation. Human Molecular Genetics 2017, 873-887.

Cornelius, N, Wardman, JH, Hargreaves, IP, Neergheen, V, Bie, AS, Tümer, Z, Nielsen, JE & Nielsen, TT. Evidence of oxidative stress and mitochondrial
dysfunction in spinocerebellar ataxia type 2 (SCA2) patient fibroblasts: Effect of coenzyme Q10 supplementation on these parameters. Mitochondrion 2017, 34: 103-114.

Frederiksen, KS. Vaskulær demens. Ugeskrift for Læger 2017: 516-521.

Gove, D, Diaz-Ponce, A, Georges, J, Moniz-Cook, E, Mountain, G, Chattat, R, Øksnebjerg, L & European Working Group of People with Dementia.
Alzheimer Europe’s position on involving people with dementia in research through PPI (patient and public involvement). Aging and Mental Health 2017: 1-7.

Hasselbalch, SG. State of the art-udredning af demens. Ugeskrift for Læger 2017: 501-504.

Herukka, S-K, Simonsen, AH, Andreasen, N, Baldeiras, I, Bjerke, M, Blennow, K, Engelborghs, S, Frisoni, GB, Gabryelewicz, T, Galluzzi, S, Handels, R, Kramberger, MG, Kulczyńska, A, Molinuevo, JL, Mroczko, B, Nordberg, A, de Oliveira, CR, Otto, M, Rinne, JO, Rot, U, Saka, E, Soininen, H, Struyfs, H, Suardi, S, Visser, PJ, Winblad, B, Zetterberg, H & Waldemar, G. ‘Recommendations for cerebrospinal fluid Alzheimer’s disease biomarkers in the diagnostic evaluation of mild cognitive impairment. Alzheimer’s & Dementia 2017, 13: 285-295.

Jensen, CS, Portelius, E, Høgh, P, Wermuth, L, Blennow, K, Zetterberg, H, Hasselbalch, SG & Simonsen, AH. Effect of physical exercise on markers of neuronal dysfunction in cerebrospinal fluid in patients with Alzheimer’s disease. Alzheimer’s & Dementia 2017, 3: 284-290. 

Johannsen, P, Gottrup, H & Stokholm, J. Frontotemporal demens. Ugeskrift for Læger 2017: 509-512 

Jørgensen, K, Johannsen, P & Vogel, A., A Danish adaptation of the Boston Naming Test: preliminary norms for older adults and validity in mild Alzheimer’s disease. Neuropsychology, Development and Cognition. Section D: The Clinical Neuropsychologist 2017: 1-16. 

Konijnenberg, E, Fereshtehnejad, S-M, Kate, MT, Eriksdotter, M, Scheltens, P, Johannsen, P, Waldemar, G & Visser, P. Early-Onset Dementia: Frequency, Diagnostic Procedures, and Quality Indicators in Three European Tertiary Referral Centers. Alzheimer Disease and Associated Disorders 2017, 31: 146.

Li, D, Secher, JO, Juhl, M, Mashayekhi, K, Nielsen, TT, Holst, B, Hyttel, P, Freude, KK & Hall, VJ. Identification of SSEA-1 expressing enhanced reprogramming
(SEER) cells in porcine embryonic fibroblasts. Cell Cycle 2017,16: 1070-1084.

Lindquist, SG, Moller, LB, Dali, CI, Marner, L, Kamsteeg, E-J, Nielsen, JE & Hjermind. A novel TTBK2 de novo mutation in a Danish family with
early-onset spinocerebellar ataxia. Cerebellum 2017, 16: 268-71.

Miller, A-M, Balasa, M, Blennow, K, Gardiner, M, Rutkowska, A, Scheltens, P, Teunissen, CE, Visser, PJ, Winblad, B, Waldemar, G & Lawlor, B. Current
Approaches and clinician attitudes to the use of cerebrospinal fluid biomarkers in diagnostic evaluation of dementia in Europe. Journal of Alzheimer’s Disease 2017, 60: 201-210.

Nabe-Nielsen, K, Garde, AH, Ishtiak-Ahmed, K, Gyntelberg, F, Mortensen, EL, Phung, TKT, Rod, NH, Waldemar, G, Westendorp, RG & Hansen, ÅM.
Shift work, long working hours, and later risk of dementia: A long-term follow-up of the Copenhagen Male Study. Scandinavian Journal of Work, Environment and Health 2017, 43: 569-577. 

Norgaard, A, Jensen-Dahm, C, Gasse, C, Hansen, ES & Waldemar, G.  Psychotropic polypharmacy in patients with Dementia: Prevalence and predictors. Journal of Alzheimer’s Disease 2017, 56: 707-716. 

Ochalek, A, Mihalik, B, Avci, HX, Chandrasekaran, A, Téglási, A, Bock, I, Giudice, ML, Táncos, Z, Molnár, K, László, L, Nielsen, JE, Holst, B, Freude, K, Hyttel, P, Kobolák, J & Dinnyés, A. Neurons derived from sporadic Alzheimer’s disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation. Alzheimer’s Research & Therapy 2017, 9: 90.

Petersen, JD, Waldorff, FB, Siersma, VD, Phung, TKT, Bebe, ACKM & Waldemar, G. Major Depressive Symptoms Increase 3-Year Mortality Rate in Patients
with Mild Dementia. Journal of Alzheimer’s Disease 2017: 7482094. Phung, TKT, Chaaya, M, Prince, M, Atweh, S, El Asmar, K, Karam, G, Khoury, RM, Ghandour, L, Ghusn, H, Nielsen, TR & Waldemar, G. Dementia prevalence, care arrangement, and access to care in Lebanon: A pilot study. Alzheimer’s & Dementia 2017, 13: 1317-1326.

Reijs, BLR, Ramakers, IHGB, Köhler, S, Teunissen, CE, Koel-Simmelink, M, Nathan, PJ, Tsolaki, M, Wahlund, L-O, Waldemar, G, Hausner, L, Vandenberghe,
R, Johannsen, P, Blackwell, A, Vanderstichele, H, Verhey, F & Visser, PJ. Memory correlates of alzheimer’s disease cerebrospinal fluid markers: A longitudinal cohort study. Journal of Alzheimer’s Disease 2017, 60: 1119-1128.

Reijs, BLR, Ramakers, IHGB, Elias-Sonnenschein, L, Teunissen, CE, Koel-Simmelink, M, Tsolaki, M, Wahlund, L-O, Waldemar, G, Hausner, L, Johannsen, P, Vanderstichele, H, Verhey, F, Devanand, DP & Visser, PJ. Relation of odor identification with alzheimer’s disease markers in cerebrospinal fluid and cognition. Journal of Alzheimer’s Disease 2017, 60: 1025-1034.

Rostgaard, N, Roos, P, Budtz-Jørgensen, E, Johannsen, P, Waldemar, G, Nørremølle, A, Lindquist, SG, Gydesen, S, Brown, JM, Collinge, J, Isaacs,
AM, Nielsen, TT, Nielsen, JE & FReJA collaboration. TMEM106B and ApoE polymorphisms in CHMP2B-mediated frontotemporal dementia (FTD-3). Neurobiology of Aging 2017, 59: 221.e1. 

Secher, JO, Ceylan, A, Mazzoni, G, Mashayekhi, K, Li, T, Muenthaisong, S, Nielsen, TT, Li, D, Li, S, Petkov, S, Cirera, S, Luo, Y, Thombs, L, Kadarmideen,
HN, Dinnyes, A, Bolund, L, Roelen, BAJ, Schmidt, M, Callesen, H, Hyttel, P & Freude, KK. Systematic in vitro and in vivo characterization of Leukemia-inhibiting factor and Fibroblast growth factor-derived porcine induced pluripotent stem cells. Molecular Reproduction and Development 2017, 84: 229-245.

Sellebjerg, F, Börnsen, L, Ammitzbøll, C, Nielsen, JE, Vinther-Jensen, T, Hjermind, LE, von Essen, M, Ratzer, RL, Soelberg Sørensen, P & Romme Christensen, J. Defining active progressive multiple sclerosis. Multiple Sclerosis 2017, 23: 1727-1735.

Simonsen, AH, Herukka, S-K, Andreasen, N, Baldeiras, I, Bjerke, M, Blennow, K, Engelborghs, S, Frisoni, GB, Gabryelewicz, T, Galluzzi, S, Handels,
R, Kramberger, MG, Kulczyńska, A, Molinuevo, JL, Mroczko, B, Nordberg, A, de Oliveira, CR, Otto, M, Rinne, JO, Rot, U, Saka, E, Soininen, H, Struyfs,
H, Suardi, S, Visser, PJ, Winblad, B, Zetterberg, H & Waldemar, G. Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia. Alzheimer’s & Dementia 2017, 13: 274-284.

Sopina, E, Sørensen, J, Beyer, N, Hasselbalch, SG & Waldemar, G. Costeffectiveness of a randomised trial of physical activity in Alzheimer’s disease: a secondary analysis exploring patient and proxy-reported health-related quality of life measures in Denmark. BMJ Open 2017, 7: e015217.

Stenbæk, DS, Fisher, PM, Ozenne, B, Andersen, E, Hjordt, LV, Mc Mahon, B, Hasselbalch, SG, Frokjaer, VG & Knudsen, GM. Brain serotonin 4 receptor binding is inversely associated with verbal memory recall. Genes, Brain and Behavior 2017, 7: e00674.

Tong, T, Ledig, C, Guerrero, R, Schuh, A, Koikkalainen, J, Tolonen, A, Rhodius-Meester, H, Barkhof, F, Tijms, BM, Lemstra, AW, Soininen, H, Remes, AM, Waldemar, G, Hasselbalch, S, Mecocci, P, Baroni, M, Lötjönen, J, Flier, WVD & Rueckert, D. Five-class differential diagnostics of neurodegenerative diseases using random undersampling boosting. NeuroImage Clinical 2017, 15: 613-624.

Waldemar, G. Ny national handlingsplan for demens. Ugeskrift for Læger 2017: 499.

Zhang, C-Y, Schmid, B, Nikolaisen, NK, Rasmussen, MA, Aldana, BI, Agger, M, Calloe, K, Stummann, TC, Larsen, HM, Nielsen, TT, Huang, J, Xu, F, Liu, X, Bolund, L, Meyer, M, Bak, LK, Waagepetersen, HS, Luo, Y, Nielsen, JE, Holst, B, Clausen, C, Hyttel, P, Freude, KK & FReJA Consortium. Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B. Stem Cell Reviews and Reports 2017, 8: 648-658.

 

 

 

 

 

Updated at 26 April 2018